MP60-06 UNCOVERING BIOLOGY OF KLINFELTER SYNDROME (47,XXY) INFERTILITY USING NOVEL 10X GENOMICS SINGLE CELL SEQUENCING
نویسندگان
چکیده
منابع مشابه
Assembly of the Complete Sitka Spruce Chloroplast Genome Using 10X Genomics’ GemCode Sequencing Data
The linked read sequencing library preparation platform by 10X Genomics produces barcoded sequencing libraries, which are subsequently sequenced using the Illumina short read sequencing technology. In this new approach, long fragments of DNA are partitioned into separate micro-reactions, where the same index sequence is incorporated into each of the sequencing fragment inserts derived from a gi...
متن کاملSimplivariate Models: Uncovering the Underlying Biology in Functional Genomics Data
One of the first steps in analyzing high-dimensional functional genomics data is an exploratory analysis of such data. Cluster Analysis and Principal Component Analysis are then usually the method of choice. Despite their versatility they also have a severe drawback: they do not always generate simple and interpretable solutions. On the basis of the observation that functional genomics data oft...
متن کاملGenomics Comes to Cell Biology
ens , in a sense the frontier has been officially closed on four of the most widely used and extensively studied species on earth. It is obvious that the closing of this frontier will open many new ones, creating directions and experimental opportunities for biologists and biomedical scientists for decades to come. However, the actual nature of these directions and opportunities remains uncerta...
متن کاملNovel approaches in function-driven single-cell genomics
Deeper sequencing and improved bioinformatics in conjunction with single-cell and metagenomic approaches continue to illuminate undercharacterized environmental microbial communities. This has propelled the 'who is there, and what might they be doing' paradigm to the uncultivated and has already radically changed the topology of the tree of life and provided key insights into the microbial cont...
متن کاملCombination of Bionano Genomics and 10x Genomics data produces high quality mammalian genome at low cost
July 25, 2017 – SAN DIEGO, CA and BETHESDA, MD – NCBI, the National Center for Biotechnology Information, has released the annotated genome assembly of the monk seal, Neomonachus schauinslandi. Bionano maps have been used to scaffold the majority of recent reference quality genomes. While these reference genomes involved costly sequencing technologies, the monk seal assembly was produced with a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Urology
سال: 2018
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2018.02.1898