Monogenic Lupus with IgA Nephropathy Caused by Spondyloenchondrodysplasia with Immune Dysregulation

Monogenic immune dysregulation syndromes

Introduction Human autoimmune diseases are a major health issue, affecting up to approximately 10% of the population (1). Common human autoimmune diseases are complex disorders that arise from the interactions between polygenic risk factors and environmental factors (2). Intensive investigation of autoimmune disease genetics has the potential to offer an unbiased view of the underlying etiologi...

IgA nephropathy in a patient with systemic lupus erythematosus.

Systemic lupus erythematosus is generally recognized to be a multisystem autoimmune disease with kidney involvement. However, the occurrence of other non-lupus glomerulopathies has been rarely reported in patients with systemic lupus erythematosus. It is well known that lupus nephritis may switch over time to another class according to the World Health Organization classification. It seems like...

Patients with IgA Nephropathy

The actual state of IgA nephropathy in Japan was surveyed throughout the nation by a questionnaire. Five hundred patients were collected from 26 departments of pediatrics and 2,1 75 from 27 internal medicine. IgA nephropathy accounted for 19.2% of the children and 30.0% of the adults among primary glomerular diseases. Most of the patients, regardless children and adults, were detected by chance...

IgA nephropathy in systemic lupus erythematosus.

Renal involvement in systemic lupus erythematosus (SLE) is a typical manifestation of the disease. The occurrence of non-lupus nephritis in SLE patients has rarely been reported; we describe the case of a woman suffering from SLE and IgA nephropathy (IgAN). Although IgAN and lupus nephritis share some common physiopathological characteristics, their laboratory and histopathologic findings and t...

NEPHROPATHY CAUSED BY CHINESE HERBS IN IRAN