منابع مشابه
Mitochondria and cardiac hypertrophy.
• Normally, myocardial metabolism is almost exclusively aerobic. The substantial quantities of adenosine triphosphate (ATP) required for muscle contraction and the much smaller amounts necessary for the maintenance of functions such as ion transport, rhythmicity, and conduction and the synthesis of membrane and protein constituents of the myocardium are supplied almost exclusively by mitochondr...
متن کاملMitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure.
WOOD, AND ARNOLD SCHWARTZ. Mitochondria and sarcoplasmic reticulum function in cardA hypertrophy and failure. Am. J. Physiol. 224(3) : 497-502. 1973.-Mitochondria and “sarcoplasmic reticulum” cardiac relaxing system (CRS) were isolated from rabbit hearts that were in various stages of hypertrophy and failure induced by progressive stenosis of the ascending aorta. The latter was produced by Amer...
متن کاملEndonuclease G: the link between mitochondria and cardiac hypertrophy?
A recent study proposes novel functions of the long known mitochondrial endonuclease, endonuclease G (ENDOG).1 ENDOG was identified via quantitative trait loci analysis as a mediator of blood-pressure–independent cardiac hypertrophy and identified as a novel component in the mitochondrial biogenesis signaling network. Blood pressure-independent cardiac hypertrophy is commonly observed in subjec...
متن کاملMitochondria Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
Mitochondria are a major site of reactive oxygen species production, which may contribute to the development of cardiovascular disease. Protecting mitochondria from oxidative damage should be an effective therapeutic strategy; however, conventional antioxidants are ineffective, because they cannot penetrate the mitochondria. This study investigated the role of mitochondrial oxidative stress dur...
متن کاملDetection of Cardiac Hypertrophy by RVM and SVM Algorithms
The meaning of the hypertropy word is the increasing size.Heart hypertropy is symptoms of increase the thickness of the heart muscle that the left ventricular hypertrophy of them is the most common.The causes of hypertrophy heart disease are high blood pressure , aortic valve stenosis and sport activities respectively. Assessment of that by using ECG signal analysis is essential Because the ris...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1975
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.36.3.367