Mismatch negativity and low frequency oscillations in schizophrenia families

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Mismatch negativity in chronic schizophrenia and first-episode schizophrenia.

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The Mismatch Negativity (MMN) is an auditory Event- Related Potential which is generated as an automatic cerebral response to any change in the auditory stimulation that exceeds a limit corresponding to the discrimination threshold. It has been widely and consistently reported that patients with recent and chronic schizophrenia display smaller MMN amplitudes, suggesting that this component may ...

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Reduced mismatch negativity (MMN) in response to auditory change is a well-established finding in schizophrenia and has been shown to be correlated with impaired daily functioning, rather than with hallmark signs and symptoms of the disorder. In this study, we investigated (1) whether the relationship between reduced MMN and impaired daily functioning is mediated by cortical volume loss in temp...

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ژورنال

عنوان ژورنال: Clinical Neurophysiology

سال: 2012

ISSN: 1388-2457

DOI: 10.1016/j.clinph.2012.03.011