منابع مشابه
miR-24 in diabetes
Diabetes are common diseases threatening health worldwide. Over the past several years it has become clear that alterations in the expression of microRNA (miRNA) genes contribute to the pathogenesis of diabetes [1, 2]. miRNAs are small (~22 nt) regulatory RNA molecules that functionally modulate the activity of specific mRNA targets involving in a wide range of physiologic and pathologic proces...
متن کاملمقایسه میزان بیان miR-106a، miR-24 و miR-107 بین دوقلوهای همسان در سنین مختلف
Background and Objective: Aging like many complex traits is the result of interaction between genome and environmental factors and epigenetic mechanisms as a central connector links these two markers. So far, investigations on age-related characteristics and biomarkers predicting survival and risk of death have been carried out, none of which led to an overall consensus among the researchers. I...
متن کاملPhagocytosis in Myeloid Inflammatory Cells miR-24, miR-30b, and miR-142-3p Regulate
Micro-RNAs (miRNAs) are small noncoding RNAs that regulate various biological pathways. As their role in phagocytosis remains poorly understood, we investigated their impact on phagocytosis in myeloid inflammatory cells. Seven miRNAs (miR-24,-30b,-101, 142-3p,-652-3p,-652-5p, and-1275) that were differentially expressed during monocyte to macrophage (Mw) and monocyte to dendritic cell (DC) diff...
متن کاملp16 Translation Suppressed by miR-24
Background: Expression of the tumor suppressor p16 increases during aging and replicative senescence. Methodology/Principal Findings: Here, we report that the microRNA miR-24 suppresses p16 expression in human diploid fibroblasts and cervical carcinoma cells. Increased p16 expression with replicative senescence was associated with decreased levels of miR-24, a microRNA that was predicted to ass...
متن کاملp16INK4a Translation Suppressed by miR-24
BACKGROUND Expression of the tumor suppressor p16(INK4a) increases during aging and replicative senescence. METHODOLOGY/PRINCIPAL FINDINGS Here, we report that the microRNA miR-24 suppresses p16 expression in human diploid fibroblasts and cervical carcinoma cells. Increased p16 expression with replicative senescence was associated with decreased levels of miR-24, a microRNA that was predicted...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4795