Metabolism of Vitamin K1 (Phylloquinone) in Man
نویسندگان
چکیده
منابع مشابه
Effect of warfarin on the metabolism of phylloquinone (vitamin K1):dose-response relationships in man.
Summarg 1. The dose-response relationship between the oral anticoagulant, warfarin, and its effect on the metabolism of phylloquinone (vitamin K,) has been examined in normal male volunteer subjects. 2. In each study the subject received a single, oral dose of warfarin and, 2 h later, an intravenous injection of [l ',2'-3H2 Jphylloquinone. Changes in the metabolism of phylloquinone were assesse...
متن کاملPhylloquinone (vitamin K1) content of vegetables
Assessment of vitamin K (VK) dietary intakes has been limited by incomplete VK food composition data for the US food supply. The phylloquinone (VK-1 or vitamin K1) concentrations of a variety of geographically representative vegetables (n 1⁄4 218) were determined by reversed-phase high performance liquid chromatography with fluorescent detection. Green leafy and flower vegetables including broc...
متن کاملRemarkable Features of the Hotdog-fold Thioesterases Involved in Phylloquinone (vitamin K1) Biosynthesis
A C K N O W L E D G M E N T S 5 T A B L E O F C O N T E N T S 6 L I S T O F F I G U R E S 8 L I S T O F T A B L E S 9 C H A P T E R 1 10 L ITERATURE REVIEW PREFACE 10 CHEMISTRY OF VITAMIN K 11 OCCURRENCE AND FUNCTIONS OF VITAMIN K 12 VERTEBRATES 12 (MOST) ARCHAEA AND BACTERIA 13 PLANTS, DIATOMS, ALGAE AND CYANOBACTERIA 14 BIOSYNTHESIS OF VITAMIN K 16 BACKGROUND 16 ISOCHORISMATE SYNTHASE AND PHY...
متن کاملSite of prenylation reaction in synthesis of phylloquinone (vitamin K1) by spinach chloroplasts.
1,4-Dihydroxy-2-naphthoate [1, 21 as the crucial intermediate in the biosynthesis of menaquinones in bacteria is formed from shikimate [3] via chorismate [2] and o-succinylbenzoate [I]. Prenylation [4] and methylation [I] result in formation of menaquinones of different length of side chain. The principal steps of the synthesis of the naphthoquinone moiety are similar for both plants and bacter...
متن کاملEnhancement effects of vitamin K1 (phylloquinone) or vitamin K2 (menaquinone-4) on intestinal alkaline phosphatase activity in rats.
Alkaline phosphatase (ALP) hydrolyzes a variety of monophosphate esters into inorganic phosphoric acid and alcohol at a high optimal pH, and is thought to play an important role in phosphate metabolism. Intestinal ALP, located at the brush border of intestinal epithelial cells, is known to be affected by several kinds of nutrients, but little is known about the physiological function of intesti...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1977
ISSN: 0035-9157
DOI: 10.1177/003591577707000211