Metabolic engineering with multi-objective optimization of kinetic models

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Metabolic engineering with multi-objective optimization of kinetic models.

Kinetic models have a great potential for metabolic engineering applications. They can be used for testing which genetic and regulatory modifications can increase the production of metabolites of interest, while simultaneously monitoring other key functions of the host organism. This work presents a methodology for increasing productivity in biotechnological processes exploiting dynamic models....

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ژورنال

عنوان ژورنال: Journal of Biotechnology

سال: 2016

ISSN: 0168-1656

DOI: 10.1016/j.jbiotec.2016.01.005