Major Histocompatibility Complex related LEI0258 allelic segregation in chicken

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allelic segregation of major histocompatibility complex using lei0258 microsatellite marker in indigenous and commercial chickens

background: major histocompatibility complex (mhc) in chicken has profound influence on resistance/susceptibility to disease, and production and reproduction traits. microsatellite marker lei0258 is a genetic indicator for mhc haplotypes. recognizing diversity of mhc haplotypes in selectively bred populations will be helpful for selecting population resistant to disease and development of effec...

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Correlation in chicken between the marker LEI0258 alleles and Major Histocompatibility Complex sequences

BACKGROUND The LEI0258 marker is located within the B region of the chicken Major Histocompatibility Complex (MHC), and is surprisingly well associated with serology. Therefore, the correlation between the LEI0258 alleles and the MHC class I and the class II alleles at the level of sequences is worth investigating in chickens. Here we describe to which extent the LEI0258 alleles are associated ...

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The chicken major histocompatibility complex and disease.

The chicken major histocompatibility complex (MHC), or B complex, consists of several clusters of highly polymorphic genes, some of which are associated with disease resistance. The class I and class II antigens resemble their mammalian counterparts in the encoded protein structure. The class IV region encodes the B blood group antigens, which are readily identified by serological blood-typing....

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The major histocompatibility complex.

The major histocompatibility complex on the sixth chromosome controls expression of a complex series of cell surface antigens which comprise the human leukocyte antigen (HLA) system. These markers, beyond their importance in human organ transplantation, have been demonstrated to occur with an increased prevalence in certain disease states. The group of conditions showing the closest association...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2013

ISSN: 1664-3224

DOI: 10.3389/conf.fimmu.2013.02.00472