Maintaining Scientific Integrity in Publications

Maintaining the integrity of the scientific record.

We editors of medical journals worry that we sometimes publish studies where the declared authors have not participated in the design of the study, had no access to the raw data, and had little to do with the interpretation of the data. Instead the sponsors of the study—often pharmaceutical companies—have designed the study and analysed and interpreted the data. Readers and editors are thus bei...

Scientific publications

Scientific Publications

Misconduct in scientific publications.

Maintaining epithelial integrity

The Short stop (Shot/Kakapo) spectraplakin is a giant cytoskeletal protein, which exists in multiple isoforms with characteristics of both spectrin and plakin superfamilies. Previously characterized Shot isoforms are similar to spectrin and dystrophin, with an actin-binding domain followed by spectrin repeats. We describe a new large exon within the shot locus, which encodes a series of plakin ...