Lifestyle factors and venous thromboembolism in two cohort studies

IntroductionEvidence on the associations of lifestyle factors with venous thromboembolism (VTE) is inconsistent. We aimed to investigate modifiable VTE in women and men.MethodsWe used data from two cohorts comprising 30,137 36,193 men aged over 45 years free cancer VTE. Information was collected 1997 via a self-administrated questionnaire. cases were ascertained by linkage National Patient Register until end 2019.ResultsDuring mean 16.9-years follow-up, 1784 2043 diagnosed Compared individuals <10 min/day physical activity, multivariable hazard ratios (HRs) 0.67 (95% confidence interval (CI), 0.58, 0.79) 0.78 CI, 0.67, 0.92) >60 min/day, respectively. lowest adherence modified Dietary Approaches Stop Hypertension diet, HRs 0.87 0.75, 0.99) 0.88 0.80, 1.00) for highest adherence. In women, 1.16 1.03, 1.29) past smoker 1.28 1.14, 1.45) current compared never smoker. Alcohol coffee consumption not associated VTE.ConclusionsThis study suggests that being physically active adhering healthy diet may lower risk men. Cigarette smoking positively women.