Isoprenylated flavonoids and clerodane diterpenoids from Dodonaea viscosa
نویسندگان
چکیده
منابع مشابه
neo-Clerodane diterpenoids from the leaf exudate of Dodonaea angustifolia
Phytochemical investigation of the leaf surface exudate of Dodonaea angustifolia L.f. yielded two new neo-clerodane diterpenes, neo-clerodan-3,13-dien-16,15:18,19-diolide (mkapwanin) and 15-methoxyneo-clerodan-3,13-dien-16,15:18,19-diolide (15-methoxymkapwanin). In addition, ten known compounds were identified. The structures were determined on the basis of spectroscopic evidence. This addition...
متن کاملRapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.
Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay, using reduction of a tetrazolium salt as an indicator of bacterial metabolism. This approach enabled the identification of fractions from Dodonae...
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Three neo-clerodane diterpenoids, inermes A, B and 14,15-dihydro-15 beta-methoxy-3-epicaryoptin, have been isolated from the hexane extract of the leaves of Clerodendrum inerme in addition to an epimeric mixture of 14,15-dihydro-15-hydroxy-3-epicaryoptin. Structures of these compounds have been elucidated on the basis of spectral studies.
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OBJECTIVE To identify the antimicrobial components present in Microglossa angolensis following fractionation of the methylene chloride extract of the aerial part of this plant. MATERIALS AND METHODS The plant was dried and extracted by percolation with methylene chloride. The dry extract was fractionated and purified by silica gel column chromatography. The isolated compounds were identified ...
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Many isoprenylated flavonoids have been isolated from Japanese mulberry tree (Moraceae). Among them, kuwanons G (1) and H (2) were the first isolated active substances exhibiting a hypotensive effect. These compounds are considered to be formed through an enzymatic Diels-Alder type reaction between an isoprenyl portion of an isoprenylphenol as the diene and an alpha, beta-double bond of chalcon...
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ژورنال
عنوان ژورنال: Natural Products and Bioprospecting
سال: 2013
ISSN: 2192-2195,2192-2209
DOI: 10.1007/s13659-013-0053-4