Inhibition of recrystallization in ice by chimeric proteins containing antifreeze domains
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چکیده
منابع مشابه
Antifreeze Protein Mimetic Metallohelices with Potent Ice Recrystallization Inhibition Activity
Antifreeze proteins are produced by extremophile species to control ice formation and growth, and they have potential applications in many fields. There are few examples of synthetic materials which can reproduce their potent ice recrystallization inhibition property. We report that self-assembled enantiomerically pure, amphipathic metallohelicies inhibited ice growth at just 20 μM. Structure-p...
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Antifreeze proteins (AFPs), occurring in some polar animals, plants, fungi, and other organisms, are capable of inhibiting ice freezing at subzero temperatures. The application of AFPs can be found in medicine and industry where low temperature storage is required and ice crystallization is damaging. This includes improved protection of blood platelets and human organs at low temperature, incre...
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W hat is the toughest recognition problem in biology? Arguably, it is that faced by antifreeze or thermal hysteresis proteins. These proteins provide a broad range of organisms with protection against freezing damage by depressing, in a noncolligative manner, the freezing point of water. They do this by binding to nascent ice nuclei and inhibiting their growth (1). In other words, antifreeze pr...
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Antifreeze (glyco) proteins are produced by many cold-acclimatized species to enable them to survive subzero temperatures. These proteins have multiple macroscopic effects on ice crystal growth which makes them appealing for low-temperature applications-from cellular cryopreservation to food storage. Poly(vinyl alcohol) has remarkable ice recrystallization inhibition activity, but its mode of a...
متن کاملIdentification of Plant Ice-binding Proteins Through Assessment of Ice-recrystallization Inhibition and Isolation Using Ice-affinity Purification.
Ice-binding proteins (IBPs) belong to a family of stress-induced proteins that are synthesized by certain organisms exposed to subzero temperatures. In plants, freeze damage occurs when extracellular ice crystals grow, resulting in the rupture of plasma membranes and possible cell death. Adsorption of IBPs to ice crystals restricts further growth by a process known as ice-recrystallization inhi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1991
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)89451-4