Indentification and characterization of a tumor-associated surface antigen on human hepatoma cell line (HuH-7).
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چکیده
منابع مشابه
Protein Transfection Study Using Multicellular Tumor Spheroids of Human Hepatoma Huh-7 Cells
Several protein transfection reagents are commercially available and are powerful tools for elucidating function of a protein in a cell. Here we described protein transfection studies of the commercially available reagents, Pro-DeliverIN, Xfect, and TuboFect, using Huh-7 multicellular tumor spheroid (MCTS) as a three-dimensional in vitro tumor model. A cellular uptake study using specific endoc...
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A previously isolated endocytic trafficking mutant (TRF1) isolated from HuH-7 cells is defective in the distribution of subpopulations of cell-surface receptors for asialoorosomucoid (asialoglycoprotein receptor (ASGR)), transferrin, and mannose-terminating glycoproteins. The pleiotropic phenotype of TRF1 also includes an increased sensitivity to Pseudomonas toxin and deficient assembly and fun...
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a receptor for ALR, that may be important for signal transduction [11] . Furthermore, ALR stimulates the mitogen-activated protein kinase cascade [12] , decreases cytochrome P450, increases nuclear factorB activity [13] , induces mRNA levels of pivotal enzymes of polyamine biosynthesis and enhances polyamine levels in human hepatocytes [14] . Although the beneficial effects of ALR in liver rege...
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Hepatitis C virus (HCV) infection represents a major public health problem throughout the world. The establishment of viral replicons has enhanced our understanding of the mechanism underlying HCV replication. However, the specific virus-host cell interactions involved in HCV RNA replication are not well understood. In the present study, we isolated several human hepatoma Huh-7-derived subclone...
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Background: We aimed at evaluating the toxicity effects of low (subtoxic) concentrations of silver nanoparticles (AgNP, 5-10 nm) in human hepatoblastoma (HepG2) cell line after and during a period of about one month. Methods: XTT and MTT assays were used to draw a dose-response curve IC50 (half maximal inhibitory concentration) value of the AgNP on HepG2 cells was calculated to be 2.75-3.0 mg/l...
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ژورنال
عنوان ژورنال: Kanzo
سال: 1991
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.32.419