Impacts of environmental toxicants on male reproductive dysfunction
نویسندگان
چکیده
منابع مشابه
Human Sperm Quality and Metal Toxicants: Protective Effects of some Flavonoids on Male Reproductive Function
Objective Metals can cause male infertility through affection of spermatogenesis and sperm quality. Strong evidences confirm that male infertility in metal-exposed humans is mediated via various mechanisms such as production of reactive oxygen species (ROS). Flavonoids have antioxidant and metal chelating properties which make them suitable candidates for neutralizing adverse effects of metals ...
متن کاملHuman Sperm Quality and Metal Toxicants: Protective Effects of some Flavonoids on Male Reproductive Function
BACKGROUND Metals can cause male infertility through affection of spermatogenesis and sperm quality. Strong evidences confirm that male infertility in metal-exposed humans is mediated via various mechanisms such as production of reactive oxygen species (ROS). Flavonoids have antioxidant and metal chelating properties which make them suitable candidates for neutralizing adverse effects of metals...
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Complications of vascular diseases, including atherosclerosis, are the number one cause of death in Western societies. Dysfunction of endothelial cells is a critical underlying cause of the pathology of atherosclerosis. Lipid rafts, and especially caveolae, are enriched in endothelial cells, and down-regulation of the caveolin-1 gene may provide protection against the development of atheroscler...
متن کاملhuman sperm quality and metal toxicants: protective effects of some flavonoids on male reproductive function
objective: metals can cause male infertility through affection of spermatogenesis and sperm quality. strong evidences confirm that male infertility in metal-exposed humans is mediated via various mechanisms such as production of reactive oxygen species (ros). flavonoids have antioxidant and metal chelating properties which make them suitable candidates for neutralizing adverse effects of metals...
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toxicants.3 Following the Seveso disaster in northern Italy in 1976, a remarkable increase in the proportion of girls was reported among offspring of heavily dioxin exposed men.4 Thus, the overarching question is not whether environmental chemicals may represent a hazard to male reproductive health, but how important this hazard at exposure levels found in the general population is in compariso...
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ژورنال
عنوان ژورنال: Trends in Pharmacological Sciences
سال: 2011
ISSN: 0165-6147
DOI: 10.1016/j.tips.2011.01.001