Immuno-histochemical Expression of Cyclin D1 in Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorders, and Normal Oral Mucosa

Due to a high risk and tendency of OPMDs towards OSCC, its early detection is essential for better survival rate. Several molecular markers are available diagnosis prognostic assessments OPMDs, also evaluating aggressiveness OSCC. Objectives: To assess the immuno-histochemical expression Cyclin D1 in normal healthy oral mucosa. has significant role cell cycle control strongly linked with metastatic poorly differentiated tumour cells. Methods: The study comprised already diagnosed 20 cases mucosa cells, as control. Results: immuno-reactivity was found positive 100% OSCC but not Conclusion: A statistically observed which may indicate probability their transformation