IEEE Quantum Week 2023

Dmd053322 2018..2023

In vitro–in vivo correlation (IVIVC) of intrinsic clearance in preclinical species of rat and dog was established using the hepatocyte relay method to support high-confidence prediction of human pharmacokinetics for low-clearance compounds. Good IVIVC of intrinsic clearance was observed for most of the compounds, with predicted values within 2-fold of the observed values. The exceptions involve...

edX Quantum Cryptography : Week 0

Dmd059675 2023..2032

Cerlapirdine (SAM-531, PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine and other 5-HT6 receptor antagonists have been in clinical development for the symptomatic treatment of Alzheimer’s disease. A human absorption, distribution, metabolism, and excretion study was conducted to gain further understanding of the metabolism and disp...

Dev104240 2014..2023

Tissue homeostasis is maintained by adult stem cells, which selfrenewand give rise to differentiating cells. The generation of daughter cells with different fates is mediated by signalling molecules coming from an external niche or being asymmetrically dispatched between the two daughters upon stem cell mitosis. In the adult Drosophila midgut, the intestinal stem cell (ISC) divides to generate ...

Quantum computers - IEEE Potentials

0278-6648/02/$17.00 © 2002 IEEE IEEE POTENTIALS aster, smaller, less expensive—that’s what we want our computers to be. No matter how good a computer chip is...it’s never good enough. We all know, at least to some extent, how today’s computer works. The digital logic behind it is actually very simple and fairly intuitive: an array of 0s and 1s represents a number. One that is easy to store, man...