Identification of functional modules based on transcriptional regulation structure
نویسندگان
چکیده
منابع مشابه
Identification of functional modules based on transcriptional regulation structure
BACKGROUND Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. Clustering algorithms mostly rely on co-expression of genes, that is group together genes having similar expression profiles. RESULTS We propose to cluster genes by co-regulation rather than by co-expression. We therefore present an inference algorithm for detecting co-reg...
متن کاملIdentification of transcriptional modules in budding yeast
One focus of postgenomic research concerns the regulation of gene expression through signal transduction and combinatorial control of gene transcription. Protein-protein interactions and protein-DNA interactions provide the dynamic backbones of regulatory networks which define the complex response of a cell to different environmental conditions. More recently, large scale experiments have resul...
متن کاملthe structure of lie derivations on c*-algebras
نشان می دهیم که هر اشتقاق لی روی یک c^*-جبر به شکل استاندارد است، یعنی می تواند به طور یکتا به مجموع یک اشتقاق لی و یک اثر مرکز مقدار تجزیه شود. کلمات کلیدی: اشتقاق، اشتقاق لی، c^*-جبر.
15 صفحه اولTranscriptional Regulation by Competing Transcription Factor Modules
Gene regulatory networks lie at the heart of cellular computation. In these networks, intracellular and extracellular signals are integrated by transcription factors, which control the expression of transcription units by binding to cis-regulatory regions on the DNA. The designs of both eukaryotic and prokaryotic cis-regulatory regions are usually highly complex. They frequently consist of both...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2008
ISSN: 1753-6561
DOI: 10.1186/1753-6561-2-s4-s4