Identification of biomarkers in colon cancer based on bioinformatic analysis

Identification of an lncRNA-miRNA-mRNA interaction mechanism in breast cancer based on bioinformatic analysis

Non‑coding RNAs serve important roles in regulating the expression of certain genes and are involved in the principal biological processes of breast cancer. The majority of studies have focused on defining the regulatory functions of long non‑coding RNAs (lncRNAs) and microRNAs (miRNAs/miRs), and few studies have investigated how lncRNAs and miRNAs are transcriptionally regulated. In the presen...

Biomarkers For Colon Cancer

49 This supplement is intended to focus on biomarkers for colon cancer. Biomarkers of survival in colon cancer, detection of new colon cancer biomarkers in tissues and body fluids, and new methods for the detection and elimination of micrometastases in colon cancer are included within the supplement's scope. Biomarkers in Cancer aims to provide researchers working in this complex, quickly devel...

Bioinformatic identification of disease associated pathways by network based analysis

Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Intense efforts have been made to elucidate the pathogeny, but the molecular mechanisms of HCC are still not well understood. To identify the candidate genes in the carcinogenesis and progression of HCC, microarray datasets GSE19665, GSE33006 and GSE41804 were downloaded from Gene Expression Omnibus (GEO) database. The ...

Glycoproteomics-Based Identification of Cancer Biomarkers

Protein glycosylation is one of the most common posttranslational modifications in mammalian cells. It is involved in many biological pathways and molecular functions and is well suited for proteomics-based disease investigations. Aberrant protein glycosylation may be associated with disease processes. Specific glycoforms of glycoproteins may serve as potential biomarkers for the early detectio...