Hypoxia-Reoxygenation
نویسندگان
چکیده
منابع مشابه
Hypoxia-reoxygenation induced necroptosis in cultured rat renal tubular epithelial cell line
Objective(s): The aim of this study is to explore the potential role of hypoxia/reoxygenation in necroptosis in cultured rat renal tubular epithelial cell line NRK-52E, and further to investigate its possible mechanisms.Materials and Methods: Cells were cultured under different hypoxia-reoxygenation conditions in vitro. MTT assay was used to measure the cell proliferation...
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Ischemic cardiac injury can be substantially alleviated by exposing the heart to pharmacological agents such as volatile anesthetics before occurrence of ischemia-reperfusion. A hallmark of this preconditioning phenomenon is its memory, when cardioprotective effects persist even after removal of preconditioning stimulus. Since numerous studies pinpoint mitochondria as crucial players in protect...
متن کاملHypoxia-reoxygenation affects whole-genome expression in the newborn eye.
PURPOSE Resuscitation of newborns is one of the most frequent procedures in neonatal medicine. The use of supplementary oxygen during resuscitation of the asphyxiated newborn has been shown to be detrimental to vulnerable tissues. We wanted to assess transcriptional changes in ocular tissue after the acute use of oxygen in the delivery room in a hypoxia-reoxygenation model of the newborn mouse....
متن کاملReactive species mechanisms of cellular hypoxia-reoxygenation injury.
Exacerbation of hypoxic injury after restoration of oxygenation (reoxygenation) is an important mechanism of cellular injury in transplantation and in myocardial, hepatic, intestinal, cerebral, renal, and other ischemic syndromes. Cellular hypoxia and reoxygenation are two essential elements of ischemia-reperfusion injury. Activated neutrophils contribute to vascular reperfusion injury, yet pos...
متن کاملPrime time for JNK-mediated Akt reactivation in hypoxia-reoxygenation.
Despite continuous advances in cardiology, heart failure still remains one of the leading causes of morbidity and mortality in the world. Heart failure can be triggered by a variety of cellular changes within the myocardium leading to a loss of contractility, arrhythmias, and ventricular remodeling. For example, myocytes in a failing heart have been shown to exhibit changes in intracellular cal...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2002
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000024411.22110.aa