Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
نویسندگان
چکیده
منابع مشابه
Dangerous liaisons
Cells during mitosis and meiosis undergo chromosome condensation through a process that depends on evolutionary conserved large protein complexes known as condensins. There are two condensing complexes, condensin i and ii, each of which is composed of five subunits. Condensin i and ii play essential, yet distinct, roles in chromosome condensation and segregation during mitosis. Recent findings ...
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The endoplasmic reticulum (ER) is the principal organelle responsible for multiple cellular functions including protein folding and maturation and the maintenance of cellular homeostasis. ER stress is activated by a variety of factors and triggers the unfolded protein response (UPR), which restores homeostasis or activates cell death. Multiple studies have clarified the link between ER stress a...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2021
ISSN: 1756-9966
DOI: 10.1186/s13046-020-01824-3