Human retinal microvascular imaging using adaptive optics scanning light ophthalmoscopy

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Human retinal microvascular imaging using adaptive optics scanning light ophthalmoscopy

BACKGROUND Retinal microvascular imaging is an especially promising application of high resolution imaging since there are increasing options for therapeutic intervention and need for better structural and functional biomarkers to characterize ocular and systemic vascular diseases. MAIN BODY Adaptive optics scanning light ophthalmoscopy (AOSLO) is an emerging technology for improving in vivo ...

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We present the first scanning laser ophthalmoscope that uses adaptive optics to measure and correct the high order aberrations of the human eye. Adaptive optics increases both lateral and axial resolution, permitting axial sectioning of retinal tissue in vivo. The instrument is used to visualize photoreceptors, nerve fibers and flow of white blood cells in retinal capillaries.

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In vivo imaging of human retinal microvasculature using adaptive optics scanning light ophthalmoscope fluorescein angiography

The adaptive optics scanning light ophthalmoscope (AOSLO) allows visualization of microscopic structures of the human retina in vivo. In this work, we demonstrate its application in combination with oral and intravenous (IV) fluorescein angiography (FA) to the in vivo visualization of the human retinal microvasculature. Ten healthy subjects ages 20 to 38 years were imaged using oral (7 and/or 2...

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Imaging of vascular wall fine structure in the human retina using adaptive optics scanning laser ophthalmoscopy.

PURPOSE To improve the ability to image the vascular walls in the living human retina using multiply-scattered light imaging with an adaptive optics scanning laser ophthalmoscope (AOSLO). METHODS In vivo arteriolar wall imaging was performed on eight healthy subjects using the Indiana AOSLO. Noninvasive imaging of vascular mural cells and wall structure were performed using systematic control...

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Adaptive optics scanning ophthalmoscopy with annular pupils

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ژورنال

عنوان ژورنال: International Journal of Retina and Vitreous

سال: 2016

ISSN: 2056-9920

DOI: 10.1186/s40942-016-0037-8