Human phase response curve to a 1 h pulse of bright white light
نویسندگان
چکیده
منابع مشابه
A human phase-response curve to light.
Using 'classical' experimental protocols, a human phase-response curve (PRC) to a single 3-h bright light pulse has been established. When the light pulse was centred slightly before the time of body temperature minimum, the circadian system delayed, whilst a pulse slightly after the minimum advanced it. Maximum phase shifts were about 2 h. When light pulses over 3 successive cycles were used, ...
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The circadian pacemaker is differentially sensitive to the resetting effects of retinal light exposure, depending upon the circadian phase at which the light exposure occurs. Previously reported human phase response curves (PRCs) to single bright light exposures have employed small sample sizes, and were often based on relatively imprecise estimates of circadian phase and phase resetting. In th...
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Giri P. Krishnan,1, 2 Maxim Bazhenov,1 and Arkady Pikovsky2 1Department of Cell Biology and Neuroscience, University of California, Riverside CA, USA 2Department of Physics and Astronomy, University of Potsdam, 14476 Potsdam, Germany (Dated: May 7, 2014) Abstract In this paper, we introduce and systematically study, in terms of phase response curves (PRC), the effect of a dual pulse excitation ...
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Exogenous melatonin is increasingly used for its phase shifting and soporific effects. We generated a three pulse phase response curve (PRC) to exogenous melatonin (3 mg) by administering it to free-running subjects. Young healthy subjects (n = 27) participated in two 5 day laboratory sessions, each preceded by at least a week of habitual, but fixed sleep. Each 5 day laboratory session started ...
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Light is the dominant environmental time cue for circadian clocks. In 1998, bright, narrow-spectrum blue light exposure to the back of the knees was reported to reset the human circadian pacemaker (HCP) (1). Science recognized the widely cited report as among the top discoveries that year to “transform our ideas about the natural world” and reported that several groups had repeated the finding ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2012
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2012.227892