Human Papillomavirus (HPV) Genotyping: Automation and Application in Routine Laboratory Testing
نویسندگان
چکیده
منابع مشابه
Human Papillomavirus (HPV) Genotyping: Automation and Application in Routine Laboratory Testing
A large number of assays designed for genotyping human papillomaviruses (HPV) have been developed in the last years. They perform within a wide range of analytical sensitivity and specificity values for the different viral types, and are used either for diagnosis, epidemiological studies, evaluation of vaccines and implementing and monitoring of vaccination programs. Methods for specific genoty...
متن کاملApplication of Chromogenic In Situ Hybridization (CISH) for Human Papillomavirus (HPV) Genotyping
Obvious decreasing in cervical cancer mortality has been observed in countries with organized cervical cancer screening programs [1]. Liquid based cytology is a technique that enables cells to be suspended in liquid medium and spread in monolayer for better morphological assessment. It includes the preparation and evaluation of cells collected in liquid fixative. It is being introduced to impro...
متن کاملUniversal human papillomavirus genotyping by the digene HPV Genotyping RH and LQ Tests.
BACKGROUND High-risk (hr)HPV testing plays an important role in primary cervical cancer screening. Subsequent hrHPV genotyping might contribute to better risk stratification. The majority of hrHPV tests do not include identification of individual hrHPV genotypes. OBJECTIVES The digene HPV Genotyping RH Test (strip-based) and LQ Test (xMAP-based) allow genotyping of GP5+/6+ amplimers, but thei...
متن کاملEvaluation of the SPF10-INNO LiPA human papillomavirus (HPV) genotyping test and the roche linear array HPV genotyping test.
The need for accurate genotyping of human papillomavirus (HPV) infections is becoming increasingly important, since (i) the oncogenic potential among the high-risk HPV genotypes varies in the pathogenesis of cervical cancer, (ii) monitoring multivalent HPV vaccines is essential to investigate the efficiency of the vaccines, and (iii) genotyping is crucial in epidemiologic studies evaluating HPV...
متن کاملCan human papillomavirus (HPV) genotyping classify non-16/18 high-risk HPV infection by risk stratification?
OBJECTIVE Infection with high-risk genotypes of human papillomavirus (HR-HPV) is the major cause of invasive cervical cancers. HPV-16 and HPV-18 are known to be responsible for two-thirds of all invasive cervical carcinomas, followed by HPV-45, -31, and -33. Current guidelines only differentiate HPV-16/18 (+) by recommending direct colposcopy for treatment. We tried to evaluate whether there ar...
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ژورنال
عنوان ژورنال: The Open Virology Journal
سال: 2012
ISSN: 1874-3579
DOI: 10.2174/1874357901206010144