High positive end-expiratory pressure during ex vivo lung perfusion: recruiting rejected donor lungs
نویسندگان
چکیده
منابع مشابه
Positive end-expiratory pressure.
PURPOSE OF REVIEW In the last 2 years, several reports have dealt with recruitment/positive end-expiratory pressure (PEEP) selection. Most of them confirm previous results and few add new information. RECENT FINDINGS It has been definitely confirmed that opening pressures are different throughout the acute respiratory distress syndrome lung parenchyma, ranging from 5-10 up to 30-40 cmH2O. The...
متن کاملPyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia
Damaged lung grafts obtained after circulatory death (DCD lungs) and warm ischemia may be at high risk of reperfusion injury after transplantation. Such lungs could be pharmacologically reconditioned using ex-vivo lung perfusion (EVLP). Since acute inflammation related to the activation of nuclear factor kappaB (NF-κB) is instrumental in lung reperfusion injury, we hypothesized that DCD lungs m...
متن کاملPerfusion of the interventricular septum during ventilation with positive end-expiratory pressure.
OBJECTIVE To determine whether regional hypoperfusion of the interventricular septum occurs during ventilation with positive end-expiratory pressure. DESIGN Animal study. ANIMALS Anesthetized, closed chest dogs (n = 8). INTERVENTIONS Induction of experimental adult respiratory distress syndrome (ARDS) and then ventilation with 10, 15, and 20 cm H2O of positive end-expiratory pressure. M...
متن کاملAirway mechanosensor behavior during application of positive end-expiratory pressure.
BACKGROUND Positive end-expiratory pressure (PEEP) is commonly used in clinical settings. It is expected to affect the input from slowly adapting pulmonary stretch receptors (SARs), leading to altered cardiopulmonary functions. However, we know little about how SARs behave during PEEP application. OBJECTIVES Our study aimed to characterize the behavior of SARs during PEEP application. METHO...
متن کاملApplication of positive end expiratory pressure during laparoscopic surgery
provided the original work is properly cited. CC Positive-pressure ventilation during general anesthesia is a prerequisite for numerous surgical conditions. Mechanical ventilation is non-physiological and can induce lung injury, although ventilator-induced lung injury may be of minor clinical importance during anesthesia for most patients with healthy lungs. However, growing evidence suggests t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Interactive CardioVascular and Thoracic Surgery
سال: 2018
ISSN: 1569-9293,1569-9285
DOI: 10.1093/icvts/ivy041