HES6 promotes prostate cancer aggressiveness independently of Notch signalling
نویسندگان
چکیده
منابع مشابه
HES6 promotes prostate cancer aggressiveness independently of Notch signalling
Notch signalling is implicated in the pathogenesis of a variety of cancers, but its role in prostate cancer is poorly understood. However, selected Notch pathway members are overrepresented in high-grade prostate cancers. We comprehensively profiled Notch pathway components in prostate cells and found prostate cancer-specific up-regulation of NOTCH3 and HES6. Their expression was particularly h...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2015
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.12537