HELICOBACTER PYLORI AND t(11;18)(q21;q21) TRANSLOCATION IN GASTRIC MALT LYMPHOMA
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori Strains and Gastric MALT Lymphoma
This article summarizes the main findings concerning Helicobacter pylori associated with gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence factor profile appear to be less virulent than those associated with peptic ulcers or gastric adenocarcinoma. A particular Lewis antigen profile has been identified in GML strains and could represent an alternative adapti...
متن کاملGastric MALT lymphoma and Helicobacter pylori.
The majority of low grade gastric lymphomas arise within acquired organized lymphoid tissue, which has all the features of MALT. This MALT is specifically acquired most commonly in response to infection of the gastric mucosa by H pylori. The lymphocytes within this MALT are therefore programmed to respond to this organism and the neoplastic cells of the lymphoma that may develop within this acq...
متن کاملHelicobacter pylori infection and gastric MALT lymphoma.
Helicobacter pylori infection is implicated in the development of two different gastric cancers: gastric adenocarcinoma and gastric MALT lymphoma. The association with the gastric MALT lymphoma is strong and causal. It is currently the only cancer which can be treated by a simple antibiotic treatment. However, the evolution of an H. pylori infection towards lymphoma is exceptional. Host suscept...
متن کاملHelicobacter pylori and t(11;18)(q21;q21) translocation in gastric malt lymphoma.
CONTEXT Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is clearly associated with Helicobacter pylori gastritis and can be cured with anti- H pylori therapy alone. The presence of t(11;18)(q21;q21) translocation is thought to predict a lower response rate to anti- H pylori treatment. OBJECTIVES To study the presence of t(11;18)(q21;q21) genetic translocation and its clinical impact...
متن کاملHelicobacter pylori Infection, Chronic Inflammation, and Genomic Transformations in Gastric MALT Lymphoma
Nowadays, it is believed that the main role in the development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma plays Helicobacter pylori infection. This world-wide distributed bacteria is in charge of most cases of not only upper gastrointestinal tract disorders but also some of extragastric problems. Constant stimulation of the immune system causes a B-lymphocytes proliferation, w...
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ژورنال
عنوان ژورنال: Arquivos de Gastroenterologia
سال: 2014
ISSN: 0004-2803
DOI: 10.1590/s0004-28032014000200003