Handheld imaging photonic crystal biosensor for multiplexed, label-free protein detection
نویسندگان
چکیده
منابع مشابه
Handheld imaging photonic crystal biosensor for multiplexed, label-free protein detection.
We present a handheld biosensor system for the label-free and specific multiplexed detection of several biomarkers employing a spectrometer-free imaging measurement system. A photonic crystal surface functionalized with multiple specific ligands forms the optical transducer. The photonic crystal slab is fabricated on a glass substrate by replicating a periodic grating master stamp with a period...
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We review the development and application of nanostructured photonic crystal surfaces and a hyperspectral reflectance imaging detection instrument which, when used together, represent a new form of optical microscopy that enables label-free, quantitative, and kinetic monitoring of biomaterial interaction with substrate surfaces. Photonic Crystal Enhanced Microscopy (PCEM) has been used to detec...
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The label-free detection of one of the cardiac biomarkers, myoglobin, using a photonic-crystal-based biosensor in a total-internal-reflection configuration (PC-TIR) is presented in this paper. The PC-TIR sensor possesses a unique open optical microcavity that allows for several key advantages in biomolecular assays. In contrast to a conventional closed microcavity, the open configuration allows...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2015
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.6.003724