H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus
نویسندگان
چکیده
منابع مشابه
Poultry farms as a source of avian influenza A (H7N9) virus reassortment and human infection
Live poultry markets are a source of human infection with avian influenza A (H7N9) virus. On February 21, 2014, a poultry farmer infected with H7N9 virus was identified in Jilin, China, and H7N9 and H9N2 viruses were isolated from the patient's farm. Reassortment between these subtype viruses generated five genotypes, one of which caused the human infection. The date of H7N9 virus introduction ...
متن کاملA new reassortment of influenza A (H7N9) virus causing human infection in Beijing, 2014
A 73-year-old man was confirmed to have an influenza A (H7N9) virus infection, and the causative agent A/Beijing/02/2014(H7N9) virus was isolated. Genetic and phylogenetic analyses revealed that the virus belonged to a novel genotype, which probably emerged and further reassorted with other H9 or H7 viruses in poultry before transmitting to humans. This virus caused a severe infection with high...
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The fragmented nature of the influenza A genome allows the exchange of gene segments when two or more influenza viruses infect the same cell, but little is known about the rules underlying this process. Here, we studied genetic reassortment between the A/Moscow/10/99 (H3N2, MO) virus originally isolated from human and the avian A/Finch/England/2051/91 (H5N2, EN) virus and found that this proces...
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Avian influenza A(H7N9) virus re-emerged in China in December 2013, after a decrease in the number of new cases during the preceding six months. Reassortment between influenza A(H7N9) and local H9N2 strains has spread from China's south-east coast to other regions. Three new reassortments of A(H7N9) virus were identified by phylogenetic analysis: between A(H7N9) and Zhejiang-derived strains, Gu...
متن کاملRapid reassortment of internal genes in avian influenza A(H7N9) virus.
TO THE EDITOR—H7N9 is a novel avian virus recently first reported from Shanghai in China. Very recently an isolate from Taiwan was also reported [1]. H7N9 is able to infect humans and has caused many fatal cases [2, 3]. Determining the origin and evolution of these disease-causing viruses is important for surveillance and prevention of the influenza epidemics. With more and more reported pathog...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2019
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1818494116