Gestational Trophoblastic Disorders: An Update in 2015
نویسندگان
چکیده
منابع مشابه
Gestational Trophoblastic Disorders: An Update
Gestational trophoblastic diseases (GTD) are a group of pregnancy-related disorders representing rare human tumours. They encompass premalignant disorders including complete (CHM), partial hydatidiform mole (PHM), exaggerated placental site (EPS), and placental-site nodule (PSN) as well as malignant disorders (also known as “gestational trophoblastic neoplasia [GTN]”) including invasive mole, c...
متن کاملEvaluation of maternal thyroid autoimmune status in gestational trophoblastic disorders
Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors, either hydatidiform mole or choriocarcinoma (1). In the US, hydatidiform mole occurs between 0.5 and 2.5 per 1000 pregnancies (2). It is more common in Asian and Latin American countries (3). Hydatidiform moles secrete large amounts of human chorionic gonadotropin (hCG), and the hCG level...
متن کاملUpdate on the diagnosis and management of gestational trophoblastic disease.
a Department of Obstetrics and Gynecology, University of Hong Kong, Queen Mary Hospital, Hong Kong, China b Departments of Histopathology and Medical Oncology, Charing Cross Trophoblastic Disease Center, Charing Cross campus of Imperial College London, London, UK c Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institu...
متن کاملGestational trophoblastic neoplasia.
Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier. Choriocarcinoma (CCA), the most common malignant form of trophoblastic disease, represente...
متن کاملGestational Trophoblastic Disease
In partial molar pregnancies, the trophoblast cells have three sets of chromosomes (triploid). Two sperm are believed to fertilise the ovum at the same time, leading to one set of maternal and two sets of paternal chromosomes. Around 10% of partial moles are tetraploid or mosaic in nature. There is usually evidence of fetal tissue or fetal blood cells in a partial molar pregnancy. An embryo may...
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ژورنال
عنوان ژورنال: Geburtshilfe und Frauenheilkunde
سال: 2015
ISSN: 0016-5751,1438-8804
DOI: 10.1055/s-0035-1558054