Genomic Alterations in Blastic Natural Killer/Extranodal Natural Killer-Like T Cell Lymphoma with Cutaneous Involvement
نویسندگان
چکیده
منابع مشابه
Primary cutaneous blastic natural killer cell lymphoma.
Sir, Blastic natural killer-cell lymphoma, also called “agranular CD4+ CD56+ haematodermic neoplasm” is an uncommon type of tumour, which is included in the new World Health Organization (WHO) classification as a malignancy derived from natural killer (NK) cells. It is very aggressive, affecting many organs, and skin involvement is highly characteristic. Several origins have been proposed, but ...
متن کاملBlastic CD56+ natural killer-cell lymphoma with primary cutaneous manifestation.
T/natural killer-cell lymphomas belong to a heterogeneous group of non-Hodgkin lymphomas with predominant extranodal, often cutaneous, manifestations. In contrast to B- and T-cell lymphomas, T/NK-cell lymphomas were only recently regarded as a distinct entity. These rather aggressive malignancies arise from cytotoxic T cells, NK-cells or NK-like T cells, which share several phenotypic and funct...
متن کاملAggressive natural killer cell leukemia or extranodal NK/T cell lymphoma? a case with nasal involvement
BACKGROUND Aggressive natural killer cell leukemia/lymphoma (ANKL) is a rare and highly aggressive NK cell neoplasm with a short clinical course and poor prognosis and is often misdiagnosed and confused with NK/T cell lymphoma (NKTL), which has a very different prognosis. Here, we present a case with nasal and bone marrow involvement, provide a literature review and make a differential diagnosi...
متن کاملEsophageal natural killer (NK)/T cell lymphoma of true natural killer cell origin.
A 53-year-old man with no prior medical history was transferred to our hospital because of a 2-month history of dysphagia with throat pain. A complete blood count showed hemoglobin 14.2g/dL, and white blood cell count 11890/mL, and other laboratory findings were within normal limits. An enhanced computed tomography (CT) scan showed diffuse thickening of the esophageal wall without regional lymp...
متن کاملExtranodal Natural Killer/T-cell lymphoma, nasal type with bilateral breast involvement - A case report
Extranodal natural killer/T cell (NK/T cell) lymphoma (ENKTL), nasal type, is a rare non-Hodgkin lymphoma originating in the nasal cavity or in the paranasal sinuses. It can involve the skin, gastrointestinal tract, soft tissue, and testis, but involvement of breast is rare. Herein we report a case of extranodal NK/T cell lymphoma with bilateral breast involvement in a middle aged female. The u...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2003
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2003.12406.x