منابع مشابه
Piperidine alkaloids: human and food animal teratogens.
Piperidine alkaloids are acutely toxic to adult livestock species and produce musculoskeletal deformities in neonatal animals. These teratogenic effects include multiple congenital contracture (MCC) deformities and cleft palate in cattle, pigs, sheep, and goats. Poisonous plants containing teratogenic piperidine alkaloids include poison hemlock (Conium maculatum), lupine (Lupinus spp.), and tob...
متن کاملTeratogens in the human: current problems.
Drugs administered to the mother can affect the fetus by preventing implantation or by causing resorption of the embryo, abortion or intrauterine death. It is a sobering thought that the first of these mechanisms is dignified by the name 'contraception' and that the remainder have far less medicolegal and economic significance than the survival of a defective fetus after a less drastic chemical...
متن کاملToxic plants as possible human teratogens
r r a t o g e n s are substances that cause birth defects. Although nongenetic deformities have been recorded throughout human history, evidence that they could be caused by exposure to toxic chemicals did not appear until the 1930s, and it was the 1961 Thalidomide episode that generated today’s public concern over teratogenic chemicals. Compounds as chemically diverse as vitamin D, quinine, as...
متن کاملTeratogens and Their Effects
A congenital malformation is an anatomical or structural abnormality present at birth. Congenital malformations may be caused by genetic factors or environmental insults or a combination of the two that occur during prenatal development. Most common congenital malformations demonstrate multifactorial inheritance with a threshold effect and are determined by a combination of genetic and environm...
متن کاملUnintended pregnancies and exposure to potential human teratogens.
BACKGROUND We aimed to investigate the risk factors associated with unintended pregnancies as well as the association between unintended pregnancies and potential teratogenic exposures. METHODS A cross-sectional survey was performed among women attending the Maternity School of the Samsung Cheil Hospital and Women's Health Care Center in Seoul, Korea. Demographic data, obstetric history, soci...
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ژورنال
عنوان ژورنال: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
سال: 1997
ISSN: 0027-5107
DOI: 10.1016/s0027-5107(97)00173-5