Functional consequences of perinatal exposure to3,4-methylenedioxymethamphetamine in rat brain
نویسندگان
چکیده
منابع مشابه
zingiber officinale alters 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain
objective: the spice zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. the effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (mdma) induced neurotoxicity have not yet been studied. the present study considers the effects of zingiber officinale on mdma-induced spatial memory impairment and apoptosis in the hippocampus of male...
متن کاملZingiber Officinale Alters 3,4-methylenedioxymethamphetamine-Induced Neurotoxicity in Rat Brain
OBJECTIVE The spice Zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. The effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity have not yet been studied. The present study considers the effects of Zingiber officinale on MDMA-induced spatial memory impairment and apoptosis in the hippocampus of male ...
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Androgens regulate aromatase activity in the medial preoptic area and other components of the brain circuit that mediates male sexual behavior. The levels of aromatase activity within these brain regions are greater in males than in females. As the activation of copulation requires aromatization of testosterone to estradiol, this quantitative enzymatic difference between sexes could contribute ...
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The developmental effects of exposure to various doses of buprenorphine, methadone, or water during the perinatal period were studied in the rat. Rats were exposed to buprenorphine (0.3, 1.0, or 3.0 mg/kg/day), methadone (9 mg/kg/day), and/or water prenatally, postnatally, or both pre- and postnatally, via maternally implanted osmotic minipumps. Fetal and maternal mortality and morbidity were a...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2002
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0704961