Fractionated stereotactic radiation therapy improves cranial neuropathies in patients with skull base meningiomas: a retrospective cohort study

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Fractionated stereotactic radiation therapy improves cranial neuropathies in patients with skull base meningiomas: a retrospective cohort study

BACKGROUND Skull base meningiomas commonly present with cranial neuropathies. Fractionated stereotactic radiation therapy (FSRT) has been used to treat these tumors with excellent local control, but rates of improvement in cranial neuropathies have not been well defined. We review the experience at Thomas Jefferson University using FSRT in the management of these patients with a focus on sympto...

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Fractionated stereotactic conformal radiotherapy for large benign skull base meningiomas

PURPOSE To assess the safety and efficacy of fractionated stereotactic radiotherapy (FSRT) for large skull base meningiomas. METHODS AND MATERIALS Fifty-two patients with large skull base meningiomas aged 34-74 years (median age 56 years) were treated with FSRT between June 2004 and August 2009. All patients received FSRT for residual or progressive meningiomas more than 4 centimeters in grea...

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Long-term outcomes of fractionated stereotactic radiotherapy for intracranial skull base benign meningiomas in single institution.

OBJECTIVE To investigate the outcome of linac-based fractionated stereotactic radiotherapy over the last 10 years for intracranial skull base benign meningiomas in patients who were inoperable, who had residual tumors with some components of high mitotic index after surgery and who experienced relapse of the tumor. METHODS Twenty-seven patients with intracranial skull base benign meningiomas ...

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Surgical and Radiation Treatment of Skull Base Meningiomas

Meningiomas comprise approximately 20% of adult primary intracranial neoplasms. Of these, benign meningiomas are known to have an indolent growth pattern, usually without infiltration into adjacent nervous tissue. Because meningiomas have a well-circumscribed character, surgery has historically been the preferred treatment when total resection can be achieved with reasonable morbidity. Surgical...

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Calcifying Pseudoneoplasms of the Skull Base Presenting with Cranial Neuropathies: Case Report and Literature Review

Objectives We report our institutional experience with calcifying pseudoneoplasms of the skull base that presented with cranial neuropathies. These lesions are also known as fibro-osseous lesions, cerebral calculi, or brain stones. Results One patient presented with facial numbness and retro-orbital pain secondary to compression of the maxillary branch of the trigeminal nerve at the anterior po...

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ژورنال

عنوان ژورنال: Radiation Oncology

سال: 2012

ISSN: 1748-717X

DOI: 10.1186/1748-717x-7-225