Formulation and Characterization of Glutaraldehyde Cross-Linked Chitosan Biodegradable Microspheres Loaded with Famotidine

formulation and characterization of ionotropic cross-linked chitosan microspheres for controlled release of ascorbic acid

Synthesis, Characterization, and Antibacterial Activity of Cross-Linked Chitosan-Glutaraldehyde

This present study deals with synthesis, characterization and antibacterial activity of cross-linked chitosan-glutaraldehyde. Results from this study indicated that cross-linked chitosan-glutaraldehyde markedly inhibited the growth of antibiotic-resistant Burkholderia cepacia complex regardless of bacterial species and incubation time while bacterial growth was unaffected by solid chitosan. Fur...

Formulation and Evaluation of Bupivacaine-Loaded Glutaraldehyde-Crosslinked High Molecular Weight Chitosan Microspheres

Purpose: To develop a chitosan microsphere carrier system of bupivacaine for buccal administration. Methods: Chitosan microspheres loaded with bupivacaine were prepared by emulsification technique based on glutaraldehyde cross-linking and drug-loaded chitosan microsphere were coated with polyglycolic acid (PGA) film The formulated microspheres were characterized by x-ray diffraction (XRD), diff...

Formulation and Evaluation of Cross Linked Chitosan Microspheres Containing Mitomycin-c G.vinoth Kumar*and K.anand Babu

The purpose of this research was to formulate and systematically evaluate in vitro performances of chitosan microspheres containing Mitomycin-C. Chitosan microspheres containing Mitomycin-C were prepared by simple emulsification phase separation technique using glutaraldehyde as a cross-linking agent. Results of preliminary trials indicate that volume of cross-linking agent, time for cross-link...

Isoniazid loaded chitosan microspheres for pulmonary delivery: Preparation and characterization

The objective of the present study was to entrap isoniazid, an Antitubercular drug, in cross linked chitosan matrix and study in vitro lung deposition of powdered chitosan microspheres using Andersen cascade impactor. Ionic cross linker Tripolyphospate was used to make cross linked chitosan microspheres to achieve sustained drug release. Chitosan microspheres were prepared by spray drying metho...