FLUNARIZINE TREATMENT FOR SPUR CELL ANAEMIA
نویسندگان
چکیده
منابع مشابه
Role of lipoproteins in the formation of spur cell anaemia.
The case of a patient with cirrhosis of the liver suffering from severe haemolysis accompanied by circulating ;spur cells' is described. Studies performed in an attempt to determine the cause for the abnormal shape of the erythrocytes demonstrated that the patient's serum could induce spur formation in normal compatible cells. Several lines of evidence pointed to the possibility that the factor...
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متن کاملReversibility of spur cell anemia.
A diagnosis of spur cell anemia was made. Spur cell anemia is found in end-stage alcoholic liver disease. The morphologic changes of spur cells are caused by accumulation of excess membrane cholesterol, leading to an impaired deformability and consequently a reduced red cell survival. The prognosis of patients with spur cell anemia is poor, with a median survival of a few months. Liver transpla...
متن کاملSpur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation.
BACKGROUND Following orthotopic liver transplantation (OLT) histological examination of explant livers from patients with alcoholic liver disease (ALD) sometimes shows extensive iron deposits in a distribution suggestive of homozygous haemochromatosis. AIMS To use haemochromatosis gene (HFE) assays to distinguish between ALD with notable siderosis and hereditary haemochromatosis. To evaluate ...
متن کاملMembrane lipid composition of red blood cells in liver disease: regression of spur cell anaemia after infusion of polyunsaturated phosphatidylcholine.
The morphology of red blood cells was studied in 30 patients with severe liver cirrhosis, in 10 patients with extrahepatic jaundice, and in 10 control subjects. In all the patients with extrahepatic jaundice more than 30% of red blood cells were target cells with increased resistance to osmotic lysis. In 12 patients with liver cirrhosis more than 30% of red blood cells were spur cells. The chol...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1983
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.1983.tb02857.x