Ferritin: isolation of aluminum-ferritin complex from brain.
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منابع مشابه
Isolation and characterization of Phycomyces blakesleeanus ferritin.
Ferritin was isolated from the fungus Phycomyces blakesleeanus and compared biochemically and immunologically with horse spleen ferritin. Phycomyces and horse spleen ferritins were shown to exhibit similar electrophoretic patterns on polyacrylamide gels. Both preparations yielded an identical single band on sodium dodecyl sulfate-containing polyacrylamide gels. Tryptic digests of Phycomyces fer...
متن کاملIsolation and properties of vitellogenic ferritin from snails.
The iron storage protein ferritin is the principal yolk protein in oocytes of the snails Planorbarius corneus L. and Lymnaea stagnalis L. This report gives an account of the isolation procedure and of some properties of snail ferritins. The isolation procedure includes a heat-denaturation step, gel filtration on Sepharose 6B and two ultracentrifugation steps followed by electrophoresis. Ferriti...
متن کاملEffect of Dietary Aluminum on Iron and Ferritin Metabolism
Aluminum (AI) toxicity is known to cause microcytic anemia, osteomalacia, and encephalopathy, but the mechanisms are poorly understood. Although Al is a neurotoxicant, its role in Alzheimer's disease remains controversial. One hypothesis for the toxicity of Al is that it disrupts cellular iron (Fe) homeostasis, causing iron to become cytotoxic. Cell culture studies have shown that Al suppresses...
متن کاملAcute Phase Proteins: Ferritin and Ferritin Isoforms
Ferritin is a positive acute phase reactant, exhibiting increased levels in blood during the acute phase response. Nevertheless, the precise role of ferritin as an acute phase reactant remains to be clarified. As for other acute phase proteins, ferritin is produced and secreted by hepatocytes. However, ferritin is also produced and secreted by other cell types, including macrophages and cancer ...
متن کاملSerum ferritin.
(1) Brief introduction to iron metabolism and the biochemistry of ferritin. (2) Early studies of circulating ferritin. (3) Methods for measuring serum ferritin concentrations -- immunoradiometric, radioimmuno- and enzyme-linked immuno assays based on liver or spleen ferritin -- an evaluation of these techniques. (4) Serum ferritin concentrations in normal subjects -- definition of normality -- ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1987
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.84.22.7866