Expression profile of Ki-67 in OSMF and its possible correlation with clinical and histological features

نویسندگان

چکیده

Background: Oral submucous fibrosis(OSMF) is a potentially malignant disorder (PMDs) with characteristic epithelial and connective tissue changes regarded as possessing high degree of potential. Epithelial dysplasia an important marker development from PMDs. Because agreement among oral pathologists poor regarding lesional diagnosis, Ki-67 proliferative may have place in objectively characterizing specimens. Material & Methods: The study groups included 60 patients diagnosed OSMF based on history clinical examination. After obtaining the details regard to habits manifestations, subjects were divided into Group IA IB (very early stages-Group I A, moderate advanced B). 30 without OSMF-negative control group SCC-positive control. Biopsy was taken subjected for H&E staining IHC analysis Ki-67. Results: mean count determined cases by using t test, value (37.41) higher than that (28.41) no significant difference (p = 0.0810).

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ژورنال

عنوان ژورنال: International Journal of Health Sciences (IJHS)

سال: 2022

ISSN: ['2550-6978', '2550-696X']

DOI: https://doi.org/10.53730/ijhs.v6ns2.6916