Expression of endothelin 2 and localized clear cell renal cell carcinoma
نویسندگان
چکیده
منابع مشابه
Downregulation of TMEM40 by miR-138-5p suppresses cell proliferation and mobility in clear cell renal cell carcinoma
Background: Clear cell renal cell carcinoma (ccRCC) represents approximately 70% of RCC,as the most frequent histological subtype of RCC. MiR-138-5p, a tumor-related microRNA (miRNA), has been reported to be implicated in the diverse types of human malignancies, but its role in ccRCCremains unclear. Objective: The study was designed to investigate the function...
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Objective: To identify the prognostic significance of CD147 and HIF-2α expressions in localized clear cell renal cell carcinoma (ccRCC). Methods: Tissue microarrays of 74 cases of ccRCC without distant metastasis or invasion were performed by CD147 and HIF-2α immunohistochemical staining. The expressions were qualified by intensity and percentage of tumor cells stained. Results: Increased expre...
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Introduction: Metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. The most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. Renal cell carcinoma accounts for nearly 3% of all adult malignancies. It usually metastasizes to the lungs,...
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MUC3A is a membrane-associated mucin that recent evidence reveals the role of MUC3A in pathogenesis and progression of cancers. To evaluate the association between MUC3A expression with overall survival (OS) and recurrence-free survival (RFS) in patients with localized clear-cell renal cell carcinoma (ccRCC), we retrospectively detected MUC3A expression in samples of 384 postoperative localized...
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Introduction. Bone morphogenetic protein-2 (BMP-2) is a member of BMP family of proteins. In human, it has role in skeletal repair and regeneration, as well as in heart formation. Kidneys of BMP-2 heterozygous null mutant mice have normal gross anatomy, but exhibit increased ureteric bud branching. Dysregulation of BMP-2 signaling has been suggested in carcinogenesis. Methods. We determined BMP...
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ژورنال
عنوان ژورنال: Human Pathology
سال: 2012
ISSN: 0046-8177
DOI: 10.1016/j.humpath.2011.07.011