Executive control function, brain activation and white matter hyperintensities in older adults
نویسندگان
چکیده
منابع مشابه
Memory and executive function in older adults: relationships with temporal and prefrontal gray matter volumes and white matter hyperintensities.
Forty-eight healthy adults aged 65-85 were recruited for structural magnetic resonance scans after an extensive neuropsychological battery that ensured a high degree of variability across the sample in performance on long-term memory tests, and on tests traditionally thought to rely on prefrontal cortex. Gray matter volumes were measured for three gyri in the frontal lobe (superior, middle, inf...
متن کاملLocalization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults.
BACKGROUND Because white matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) may be linked to geriatric syndromes involving mobility, cognition, and affect, we postulated that involvement of areas critical to bladder control could influence urinary incontinence (UI). METHODS One hundred community-dwelling individuals (75-89 years) were recruited into three groups stratified by ...
متن کاملEndothelial function and white matter hyperintensities in older adults with cardiovascular disease.
BACKGROUND AND PURPOSE The presence of white matter hyperintensities on brain MRI is common among elderly individuals. Previous research suggests that cardiovascular risk factors are associated with increased white matter hyperintensities. Examining the role of direct physiological measures of vascular function will help to clarify the vascular mechanisms related to white matter hyperintensitie...
متن کاملEndothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults
Age-related declines in endothelial function can lead to cognitive decline. However, little is known about the relationships between endothelial function and specific neurocognitive functions. This study explored the relationship between measures of endothelial function (reactive hyperemia index; RHI), white matter (WM) health (fractional anisotropy, FA, and WM hyperintensity volume, WMH), and ...
متن کاملWhite matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment.
UNLABELLED Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction. METHODS Twenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI indivi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: NeuroImage
سال: 2010
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2009.11.019