Evaluation of choroidal thickness and retinal nerve fiber layer thickness in patients with unilateral amblyopia: a prospective study

ABSTRACT Purpose: to compare the Subfoveal choroidal thickness (SFCT) and Retinal Nerve Fiber Layer Thickness (RNFL) of amblyopic normal fellow eyes. Design: Prospective, cross-sectional, observational case series. Methods: Forty patients age 12 41 years (mean 23.73 ± 6.42) with unilateral amblyopia were studied. Among them, 11(28.2%) had secondary strabismus 29(71.8 %) anisometropic amblyopia. Optical coherence tomography (OCT) peripapillary RNFL eyes was performed. measurements taken from superior, inferior, nasal temporal quadrants in region. Also, subfoveal measured using spectral domain optical (SD-OCT). Results: Mean global 104.48 microns 102.83 microns, respectively. The difference between two groups not statistically significant (p>0.05%). thicknesses retinal nerve fiber layer showed no However, SFCT eye 11 or more thicker than this different (p<0.05%). Conclusions: This study demonstrated significantly process may involve choroid, but prepapillary NFL.