Epigenetic targeting drugs potentiate chemotherapeutic effects in solid tumor therapy
نویسندگان
چکیده
منابع مشابه
Epigenetic therapy and chemosensitization in solid malignancy.
Epigenetic modifications result in dynamic shifts between transcriptionally active and suppressed states. The potentially reversible nature of epigenetic changes underlies the concept of epigenetic therapy, which serves to reprogram cancer cells as opposed to inducing cytotoxicity that occurs with standard chemotherapeutics. There are numerous enzymes involved in epigenetic changes and each can...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-04406-0