EP1 receptor is involved in prostaglandin E2-induced osteosarcoma growth
نویسندگان
چکیده
منابع مشابه
Targeting Prostaglandin E2 Ep1 Receptors Prevents
246 words Introduction: 534 words Discussion: 2209 words Abbreviations: COX, cyclooxygenase; COX-2, cyclooxygenase-2; TBS, tris-buffered saline; P-gp, P-glycoprotein; BBB, blood-brain barrier; PGE2, Prostaglandin E2; EEG, Electroencephalogram; NMDA, N-methyl-D-aspartic acid; CNS, central nervous system Section: Neuropharmacology This article has not been copyedited and formatted. The final vers...
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The lipid mediator prostaglandin E2 (PGE2) has diverse biological activity in a variety of tissues. Four different receptor subtypes (EP1-4) mediate these wide-ranging effects. The EP-receptor subtypes differ in tissue distribution, ligand-binding affinity, and coupling to intracellular signaling pathways. To identify the physiological roles for one of these receptors, the EP1 receptor, we gene...
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ژورنال
عنوان ژورنال: Bosnian Journal of Basic Medical Sciences
سال: 2019
ISSN: 1840-4812,1512-8601
DOI: 10.17305/bjbms.2019.4177