منابع مشابه
Melanoma resistance to photodynamic therapy: new insights.
Melanoma is the most dangerous form of skin cancer, with a steeply rising incidence and a poor prognosis in its advanced stages. Melanoma is highly resistant to traditional chemotherapy and radiotherapy, although modern targeted therapies such as BRAF inhibitors are showing some promise. Photodynamic therapy (PDT, the combination of photosensitizing dyes and visible light) has been tested in th...
متن کاملEndocrine Disruptors and Child Health: New Insights.
genitalia and poorer sperm quality, cryptorchidism, neurological effects, neuropsychiatric disorders, diabetes, obesity and other metabolic disorders have been associated with the exposure to EDs [2] . The situation has been worrying clinicians and scientists and call-to-action statements have been published [3] . EDs are divided into major classes of chemicals including various types of pestic...
متن کاملChanging the Horizon of Endocrine Therapy Resistance
7. The story of EZH2, from its discovery as a regulator of body patterning in fruit flies to the recognition of its role as a transcriptional regulator of chromatin structure and as a driver of cancer, should soon have a new chapter once clinical trials reveal whether targeting EZH2 can bring a substantial therapeutic advance. (Kim KH, Roberts CW. Targeting EZH2 in cancer. Nat Med. 2016;22(2):1...
متن کاملNew Insights Into Nonadherence With Adjuvant Endocrine Therapy Among Young Women With Breast Cancer.
Despite the well-established survival benefit associated with adjuvant endocrine treatment (ET), ensuring that breast cancer survivors adhere to the prescribed duration of therapy remains challenging. Studies have found young age to be a risk factor for nonadherence and nonpersistence to ET (1). However, little is known about the reasons why young women are less likely to take ET as prescribed,...
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results the present study revealed that the sobt and sop extracts showed in vitro bactericidal activity against gram-positive and gram-negative bacteria. furthermore, administration of sobt and sop increased the rats’ survival rates by 66.7% and 83.33%, respectively, as compared to the untreated clp-septic rats. treatment of the clp-septic rats with sobt and sop significantly alleviated alterat...
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ژورنال
عنوان ژورنال: The Breast
سال: 2019
ISSN: 0960-9776
DOI: 10.1016/s0960-9776(19)31118-x