Endocannabinoids, Blood Pressure and the Human Heart

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Endocannabinoids, blood pressure and the human heart.

The effects of exogenous and endogenous cannabinoids on the cardiovascular system have been the focus of extensive research. The direct and indirect effects of cannabinoids on heart and blood vessels depend upon experimental conditions, animal species, and, in humans, clinical background. Cannabinoids decrease blood pressure in hypertensive rodents primarily because of decrease cardiac contract...

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Blood pressure regulation by endocannabinoids and their receptors.

Cannabinoids and their endogenous and synthetic analogs exert powerful hypotensive and cardiodepressor effects by complex mechanisms involving direct and indirect effects on myocardium and vasculature. On the one hand, endocannabinoids and cannabinoid receptors have been implicated in the hypotensive state associated with hemorrhagic, endotoxic and cardiogenic shock, and advanced liver cirrhosi...

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ژورنال

عنوان ژورنال: Journal of Neuroendocrinology

سال: 2008

ISSN: 0953-8194,1365-2826

DOI: 10.1111/j.1365-2826.2008.01677.x