Enanatioselective Switch and Potential Applications in Biocatalysis
نویسندگان
چکیده
Enantioselectivity has always been a key feature of enzymatic synthesis. In some cases, when enzymes are not strictly enantioselective, by tuning the reaction conditions it is possible to induce an enantioselective switch. A transaminase from Halomonas elongata (ω-HeWT), while generally S-selective, could be shifted towards generating R-enantiomer at higher concentrations amino acceptor or ionic strength, for example. Other reported have similar behavior, and here we discuss them their potential applications.
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ژورنال
عنوان ژورنال: Chimia
سال: 2023
ISSN: ['0009-4293', '2673-2424']
DOI: https://doi.org/10.2533/chimia.2023.390