Dual antiplatelet therapy in the drug-eluting stent era
نویسندگان
چکیده
منابع مشابه
Dual antiplatelet therapy after drug-eluting stent implantation: is it time to slacken the reins?
Drug-eluting stents (DES) were introduced in interventional practice more than 10 years ago and rapidly replaced bare-metal stents (BMS) for treatment of coronary artery disease because of their superior capability to reduce the need for restenosis-driven repeat intervention. Soon, it became obvious that besides optimal stenting technique, dual antiplatelet therapy (DAPT), which means the combi...
متن کاملThe optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: chasing a mirage.
T he optimal treatment duration of aspirin and a P2Y12 receptor antagonist after percutaneous coronary intervention (PCI) has vexed cardiologists since the introduction of drug-eluting stents (DES) approximately a decade ago. A short (2to 4-week) course of aspirin and a thienopyridine after elective implantation of a bare-metal stent became the standard of care by default from randomized trials...
متن کاملDouble Antiplatelet Therapy After Drug-Eluting Stent Implantation
Ignacio Ferreira-González, MD, PHD,*† Josep R. Marsal, BSC,*†‡ Aida Ribera, PHD,*† Gaietà Permanyer-Miralda, MD, PHD,*† Bruno Garcı́a-Del Blanco, MD,* Gerard Martı́, MD,* Purificación Cascant, RN,*† Mónica Masotti-Centol, MD, PHD,§ Xavier Carrillo, MD, Josepa Mauri, PHD, Nuria Batalla, MD,¶ Eduard Larrousse, MD,# Eva Martı́n, MD,** Antonio Serra, MD,†† José Ramón Rumoroso, MD,‡‡ Rafael Ruiz-Salmer...
متن کاملClopidogrel Versus Aspirin as an Antiplatelet Monotherapy After 12-Month Dual-Antiplatelet Therapy in the Era of Drug-Eluting Stents.
BACKGROUND The use of dual-antiplatelet therapy (DAPT) exceeding 12 months may increase a bleeding risk despite a lower risk of ischemic events. There is no study to compare clinical outcomes in patients treated with a single-antiplatelet drug after DAPT in the era of drug-eluting stents (DES). We sought to investigate the efficacy and safety of clopidogrel versus aspirin monotherapy after 12-m...
متن کاملIndividualization of dual antiplatelet therapy duration after drug-eluting stent implantation: paradigm and reality.
The use of drug-eluting stents (DES) results in a dramatic reduction in restenosis and represents one of the major advances in interventional cardiology. Yet, a reduction in death and myocardial infarction could not be shown with these devices; instead there were concerns about an excess of late thrombotic events compared with bare metal stents (BMS). The key underlying pathophysiological mecha...
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2008
ISSN: 1554-2815,1520-1554
DOI: 10.1093/eurheartj/sun011