Differences between negative chrono-, dromo- and inotropic actions of cholinomimetics in the dog isolated atrium.

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Differences between negative chrono-, dromo- and inotropic actions of cholinomimetics in the dog isolated atrium.

Both bethanechol and physostigmine produced dose-dependent negative chrono-, dromo- and inotropic effects in the dog isolated atrial preparation. Within a relatively small dose of bethanechol and physostigmine, negative inotropic effect was clearly induced but no significant chrono- and dromotropic changes were observed. With a relatively large dose, the two cholinomimetics caused negative chro...

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ژورنال

عنوان ژورنال: Japanese Heart Journal

سال: 1985

ISSN: 0021-4868,1348-673X

DOI: 10.1536/ihj.26.801