Diagnostic Difficulties in Whipple's Disease
نویسندگان
چکیده
منابع مشابه
Whipples disease: a review
Whipples disease was described in 1907 and given the name intestinal lipodystrophy until it was found that the agent responsible is a bacterium named Tropheryma whipplei. Its a rare disease which occurs predominantly in males aged 30-60. The small intestinal mucosa is always affected with lesions that are specific to this disease. Replacement of most of cellular elements in the lamina propr...
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Kufs' disease or NCL4 (neuronal ceroid lipofuscinosis type 4) is a rare and poorly characterized, adult-onset form of NCL. The mutation in gene CLN, underlying Kufs' disease, still remains unknown. The diagnosis of this disease is difficult because it is based only on clinical and ultrastructural examinations. We report the case of a 45-year-old woman referred to the Neurological Department wit...
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Seven cases of ulceration of the small intestine are described and the relationship to coeliac disease is discussed. Evidence for coeliac disease is found in all cases but is less strong in some than in others, and coeliac disease was proved in only two cases. The ulcers were examined histologically in each case and in three cases were associated with malignant histiocytosis but the others show...
متن کاملPeripheral neuropathy in Whipples disease: a case report.
Whipples disease is a chronic multisystem inflammatory disease with predominantly gastrointestinal manifestations due to Tropheryma whipplei infection. Typical neurological abnormalities include dementia, eye movement abnormalities, hypothalamic dysfunction and oculomasticatory myorhythmias. The literature on peripheral neuropathy in Whipples disease is sparse and the involvement of peripheral ...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1979
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107687907201116