Development of Timd2 as a reporter gene for MRI
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Development of Timd2 as a reporter gene for MRI
PURPOSE To assess the potential of an MRI gene reporter based on the ferritin receptor Timd2 (T-cell immunoglobulin and mucin domain containing protein 2), using T1- and T2-weighted imaging. METHODS Pellets of cells that had been modified to express the Timd2 transgene, and incubated with either iron-loaded or manganese-loaded ferritin, were imaged using T1- and T2-weighted MRI. Mice were als...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2015
ISSN: 0740-3194
DOI: 10.1002/mrm.25750