Determination of Phytoconstituents and Antimicrobial activities of aqueous and methanol extracts of Neem (Azadirachta indica) leaves

Neem (Azadirachta Indica)is a plant that has been used as traditional medicine for household remedy against various human ailments since ancient times. The objective of this study was to determine the phytoconstituents and antimicrobial activities aqueous methanol extracts A. indica leaves. Qualitative quantitative phytochemical analysis carried out using standard method Association Official Analytical Chemist activity concentrated evaluated by determination diameter zone inhibition microorganisms agar well diffusion method. Phytochemical screening leaves gave positive result saponins, tannins, steroids, glycoside, terpenoids, flavonoids, alkaloids. results show both had test organisms, were found greater effect on Shigellasp (10.0±1.0 mm), Staphylococcus sp Penicilliumsp (9.2±0.8 mm) Mould (10.2±1.3 while extract shows maximum efficacy E. coli (26±1.0 Vibrio (10.6±0.6 Yeast (9.2±0.3 mm). Therefore, these findings support knowledge local users it is preliminary, scientific, validation use neem promote proper conservation sustainable resources.